Magnesium carbonate is a common digestive system API and can be used for various stomach diseases. Hebei Messi Biology Co., Ltd. said that in fact, the role of magnesium carbonate is not limited to this.
1. Neutralize gastric acid
Magnesium carbonate is an antacid, 1g of magnesium carbonate can neutralize 27.1–27.8 hydrochloric acid. The main component of human gastric juice is hydrochloric acid secreted by gastric parietal cells. Gastric acid plays an extremely important role in the digestion process of food. If gastric acid is secreted too much, it will erode the gastric mucosa and cause gastric inflammation or ulcers. Antacids are needed to neutralize excess stomach acid.
pharma grade magnesium carbonate
2. Maintain stomach pH
Magnesium carbonate can neutralize gastric acid, and it can also maintain gastric pH between 3 and 5, which is mainly due to the characteristics of magnesium carbonate. When the pH of the stomach is less than 3, magnesium carbonate starts the neutralization reaction to prevent excessive gastric acid from eroding the gastric mucosa; when the pH is 5, the reaction is terminated to avoid the intensification of gastric acid secretion caused by the high pH value in the stomach; when the pH is less than 3 , the reaction starts again, so the pH in the stomach can be kept in an appropriate range.
3. Adsorption and binding
Magnesium carbonate can directly inhibit its activity by adsorbing and binding pepsin, which is beneficial to the repair of ulcers; it can also bind bile acids and adsorb lysophosphorylcholine, thereby preventing these substances from further damage and destruction to the gastric mucosa.
4. Protect gastric mucosa
Magnesium carbonate can stimulate gastric mucosa to increase the synthesis of prostaglandin E2, and prostaglandin E2 can regulate the normal secretion of gastric acid, and also has a certain protective effect on gastric mucosa, so it can enhance the role of “gastric mucosal barrier”. In addition, magnesium carbonate can also promote the release of epidermal growth factor in the gastric mucosa, increase the content of phospholipids in the hydrophobic layer of the submucus, and prevent gastric mucosal damage caused by hydrogen ion reverse osmosis.
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